NIH-funded postdoctoral fellows or research associates are available in the laboratory of Dr. Ming You at the Houston Methodist Neal Cancer Center that is focused on cancer immunology with a specific emphasis on cancer immunoprevention using vaccines (peptides, protein, DNA or mRNA) in both mouse models and in humans. Specific areas of interest include develop and produce novel cancer vaccines and characterize the vaccines for safety, immune response and efficacy preclinically using genetically modified mouse models, flow cytometry, q-PCR, RNA-seq, western blot, single cell RNA seq, and other immunological techniques.
NIH-funded postdoctoral fellows or research associates are available in the laboratory of Dr. Ming You at the Houston Methodist Neal Cancer Center that is focused on development and characterization of novel mitochondria-targeting compounds for cancer prevention. Specifically, we are interested in individuals with expertise in targeting small molecules to mitochondria by attaching these compounds to a lipophilic cation such triphenylphosphonium, or in the characterization of these mitochondria-targeting agents for their antitumor efficacy using both in vitro and in vivo systems. Methods will be used including organic synthesis, cell proliferation measurements with IncuCyte Live-Cell Analysis system, mitochondrial oxygen consumption measurements with the Seahorse XF-96 Extracellular Flux Analyzer, and methods to determine metabolic changes in the tumor microenvironment.
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